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- 1/200 of the biomass threshold
- A “Proteomic Ruler” for Protein Copy Number and Concentration Estimation without Spike-in Standards
- A comparison between the sulfhydryl reductants tris(2-carboxyethyl)phosphine and dithiothreitol for use in protein biochemistry
- A comprehensive review on Optimal conditions for carrying out trypsin digestions on complex proteomes
- A new view of the tree of life
- A Proteomics Approach to the Protein Normalization Problem: Selection of Unvarying Proteins for MS-Based Proteomics and Western Blotting
- A Simple Elution Strategy for Biotinylated Proteins Bound to Streptavidin Conjugated Beads using Excess Biotin and Heat
- A two-step database search method improves sensitivity in peptide sequence matches for metaproteomics and proteogenomics studies
- About Perseus
- Accurate Mass Spectrometry Based Protein Quantification via Shared Peptides
- Accurate multiplexed proteomics at the MS2 level using the complement reporter ion cluster
- Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ
- Accurate, Sensitive, and Precise Multiplexed Proteomics Using the Complement Reporter Ion Cluster
- Acquisition and Analysis of DIA-Based Proteomic Data: A Comprehensive Survey in 2023
- Advancement in protein inference from shotgun proteomics using peptide detectability
- Advances in the clinical use of metaproteomics
- AFA: Adaptive Focused Acoustics
- AI learning tools
- Alessandro Tanca
- all ion fragmentation
- Amazing performance on Astral
- AMR database
- An old method facing a new challenge: re-visiting housekeeping proteins as internal reference control for neuroscience research
- Anaerostipes hadrus
- Antimicrobial peptides (AMPs)
- Assessing species biomass contributions in microbial communities via metaproteomics
- Astral Applications
- Astral MS
- Automated sample preparation with SP3 for low‐input clinical proteomics
- AVrC: Aggregated Gut Viral Catalogue
- backlink footer template
- Bacterial Cell sorting on flow cytometry
- bacterial species
- Benjamin Orsburn
- Beyond protein lists: AI-assisted interpretation of proteomic investigations in the context of evolving scientific knowledge
- Bias in False Discovery Rate Estimation in Mass-Spectrometry-Based Peptide IdentificationClic
- Big Names
- Bing Zhang
- BioID
- Bioinformatic tools for Metaproteomics
- biomass difference
- Bookmarks
- Brian C. Searle
- CamelCase Links
- Candida albicans
- Cazy
- CAZymes
- CDF normalization
- CGR2: The genomic landscape of reference genomes of cultivated human gut bacteria
- Challenging the Astral mass analyzer to quantify up to 5,300 proteins per single cell at unseen accuracy to uncover cellular heterogeneity
- Christina Ludwig
- Cladogram
- CNN explainer
- COG
- color code in maxquant output
- column dimension and peak width
- Column Regeneration
- combine peptide probability to protein level
- Community ecology as a framework for human microbiome research
- composition of dry human feces
- compositional data
- Consistency with the concept of nestedness
- Constructing a dietary protein database
- cool app
- Core facilities
- core facilities in uottawa
- correlation analysis
- Correlation: Pearson VS Spearman
- CRAN Task Views
- Cursor rules
- Data-independent acquisition boosts quantitative metaproteomics for deep characterization of gut microbiota
- Data-Independent Acquisition Mass Spectrometry in Metaproteomics of Gut Microbiota—Implementation and Computational Analysis
- Data-independent acquisition: A milestone and prospect in clinical mass spectrometry-based proteomics
- database for human gut metaproteomics
- David Gómez-Varela
- David L. Tabb
- dbCAN-seq
- DBCGR2
- DBReducer
- DDIA
- DDM
- De Novo from DIA
- Dear-DIAXMBD: Deep Autoencoder Enables Deconvolution of Data-Independent Acquisition Proteomics
- Deciphering functional redundancy in the human microbiome
- Decoy database searches are problematic for large database
- Deep learning
- DeepDetect
- DeepDIA
- DIA analysis tool
- DIA for metaproteomics
- DIA for tongue coating for gastric cancer
- DIA history
- DIA metaproteomics on Astral
- DIA on gut microbiome from colorectal cancer
- DIA pushes proteomics from spectrum centric to peptide centric
- DIA VS TMT
- DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput
- DIA-Umpire
- Diann key parameters
- diann result and filtering
- DIANN's more technical details
- Digestion after BioID
- directDIA
- directLFQ
- DirectMS1: MS/MS-Free Identification of 1000 Proteins of Cellular Proteomes in 5 Minutes
- dissociation constant
- Diversity
- DMSO enchance Microflow through Postcolumn Addition
- DMSO enchances ESI
- download.jpg
- download.png
- Draft of 'Hyungwon Choi' by Beshy
- Draft of 'New Tiddler' by Beshy
- Draft of 'Posterior error probabilities and false discovery rates: two sides of the same coin' by Beshy
- Dynamic Data Independent Acquisition
- EASI-tag enables accurate multiplexed and interference-free MS2-based proteome quantification
- EasyPhos in 2018
- Efficient generation of open multi-stage fragmentation mass spectral libraries
- Emma Allen-Vercoe
- EncyclopeDIA
- epoch, iteration, batch size
- ESI commercials
- Estimating relative biomasses of organisms in microbiota using phylopeptidomics
- Estimating the confidence of peptide identifications without decoy databases
- Evaluating False Transfer Rates from the Match-between-Runs Algorithm with a Two-Proteome Model
- Evaluation of FASP, SP3, and iST Protocols for Proteomic Sample Preparation in the Low Microgram Range
- Extensive DIA method comparison
- False Discovery Rates and Related Statistical Concepts in Mass Spectrometry-Based Proteomics
- fast DIA outperforms TMT for metaproteomics
- fav.png
- FDR accumulation in proteomics
- Fight: why we need metaproteomics?
- Fisher's 精确检验
- fractionation on Astral DIA
- Frequent used online tools
- frequently used
- Fully Automated Workflow for Integrated Sample Digestion and Evotip Loading Enabling High-Throughput Clinical Proteomics
- Function is what counts
- functional redundancy
- Functional Redundancy Instead of Species Redundancy Determines Community Stability in a Typical Steppe of Inner Mongolia
- Fusobacterium nucleatum
- gene content network
- Generating image by AI
- genome size
- glaDIAtor
- Global compositional and functional states of the human gut microbiome in health and disease
- glycan utilization loci
- GNPS
- Good dataset
- Good Figures
- GSEA analysis
- GSVA
- Guild and Niche Determination Enable Targeted Alteration of the Microbiome
- Guild and niche in microbiome
- Guild-based analysis for understanding gut microbiome in human health and diseases
- Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes
- Gut microbiota composition correlates with diet and health in the elderly
- gut virome
- H2O AutoML
- Hamilton liquid handler learning
- HDF5
- Heather Armstrong
- High-throughput proteomic sample preparation using pressure cycling technology
- HILIC
- Hill Numbers
- Housekeeping proteins: a preliminary study illustrating some limitations as useful references in protein expression studies
- how many missing values are there in DDA/DIA
- How to speed up the tryptic digestion?
- How to talk about protein‐level false discovery rates in shotgun proteomics
- Hugging Face
- hugging face chat
- Hybrid-DIA
- Hyungwon Choi
- Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes
- image.png
- In Search of a Universal Method: A Comparative Survey of Bottom-Up Proteomics Sample Preparation Methods
- Increasing the power of interpretation for soil metaproteomics data
- Increasing the throughput of sensitive proteomics by plexDIA
- Individual species provide multifaceted contributions to the stability of ecosystems
- iNEXT
- Instrumentation at the Leading Edge of Proteomics
- Interesting fact
- IonQuant Enables Accurate and Sensitive Label-Free Quantification With FDR-Controlled Match-Between-Runs
- iq: an R package to estimate relative protein abundances from ion quantification in DIA-MS-based proteomics
- Jacek R. Wisniewski
- Jana Seifert
- Jean Armengaud
- Jesper V. Olsen
- Journals of interest
- Juergen Cox
- kernel estimation for CDF
- key questions about SP3
- KingFisher Flex System
- KOLMOGOROV–SMIRNOV TEST
- Krona
- Laura Elo
- LC configure
- Lennart Martens
- LFQRatio
- Liang Qiao
- Liang Tian
- literature reading
- Lloyd M Smith
- loss of microbial cross feeding interactions
- Lukas Käll
- machine learning dataset
- Machine learning VS deep learning
- magnetic HILIC beads
- Manuel Kleiner
- Markup Reference
- Marsilea: Declarative creation of composable visualization
- Martin Wühr
- Mass spectrometrists should only search for peptides they care about
- Mass spectrometrists should search for all peptides, but assess only the ones they care about
- MBR: match between run
- MDA
- Measuring turbidity
- Meta4P
- metacoder
- MetaCoder
- MetaNovo
- Metaproteomic portrait of the healthy human gut microbiota
- Metaproteomics and DNA metabarcoding as tools to assess dietary intake in humans
- Metaproteomics Initiative
- Metaproteomics to understand how microbiota function: The crystal ball predicts a promising future
- Michael J. MacCoss
- MiCId: Microorganism Classification and Identification
- microbiome composition difference
- microbiome relationship
- Milestones of Metaproteomics
- miniPhos in 2023
- Mirror: An LLM-powered programming-by-example programming language
- Modeling Lower-Order Statistics to Enable Decoy-Free FDR Estimation in Proteomics
- MS QC tools
- MS-DIAL
- MS2Bac
- MS²Rescore
- mTRAQ
- Mycoplasma
- mzmine3
- nanoLC design
- network of big names
- NeuCode Labels for Relative Protein Quantification
- Nikolai Slavov
- Non-mechanical disruption of Bacillus subtilis spores allows sensitive and deep characterization of the minimal proteome for resuming a cellular lifestyle
- Nonlinear fitting method for determining local false discovery rates from decoy database searches
- Not All About Proteomcs
- Notes for Vanquish Neo HPLC
- Oliver Fiehn
- On the potential of micro-flow LC-MS/MS in proteomics
- Only metaproteomics can inspect biomass based quantificiation
- optimization of SP3 by the original author
- Optimized Automated Workflow for BioID
- Orbitrap Astral for Metabolomics
- orochem.com
- p value correction for multiple testing
- PAcIFIC
- Parallelized Acquisition of Orbitrap and Astral Analyzers Enables High-Throughput Quantitative Analysis
- Pavel A Pevzner
- PCA在R以及PCA 的数学意义解读
- PCoA VS PCA
- PECAN
- PEP
- PepGM
- PepQuery
- PepQuery2
- peptide detectability: standard and effective
- PeptideMapper
- Peptonizer2000
- Percolator
- Perspective
- Perspective and Guidelines for Metaproteomics in Microbiome Studies
- Phosphopeptide enrichment Review
- phyloseq
- Picked Protein FDR
- plagiarism figure by figure
- Posterior error probabilities and false discovery rates: two sides of the same coin
- Pratik Jagtap
- predicted peptide detectability
- Prediction of peptide mass spectral libraries with machine learning
- Probability 概率
- Prodigal
- Protein Aggregation Capture on Microparticles Enables Multipurpose Proteomics Sample Preparation
- Protein Contaminants Matter
- protein digestion
- ProteoBench
- ProteoClade
- Proteome depth reached in single-cell experiments
- Proteomic stable isotope probing
- Proteomics on an Orbitrap benchtop mass spectrometer using all-ion fragmentation
- prozor
- PTXQC
- q value
- quantile normalization
- QuantUMS
- Qwen2
- Qwen2.5-Coder
- Rarefaction
- razor peptide
- reflection on Astral
- report
- resilience vs resistance
- Revealing proteome-level functional redundancy in the human gut microbiome using ultra-deep metaproteomics
- roadmap: learning resource
- Robust and Easy-to-Use One-Pot Workflow for Label-Free Single-Cell Proteomics
- Robust Capillary- and Micro-Flow Liquid Chromatography–Tandem Mass Spectrometry Methods for High-Throughput Proteome Profiling
- Robust Microflow LC-MS/MS for Proteome Analysis: 38 000 Runs and Counting
- Robust, Precise, and Deep Proteome Profiling Using a Small Mass Range and Narrow Window Data-Independent-Acquisition Scheme
- Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS
- Russians in proteins
- Sage
- Sample Preparation by Easy Extraction and Digestion (SPEED) - A Universal, Rapid, and Detergent-free Protocol for Proteomics Based on Acid Extraction
- sample preservation
- scanning quadrupole
- SCX for SDS cleanup
- sequence of gluten peptide that are resistant to digestion
- shared peptide problem for protein inference
- SIMSI-Transfer: Software-Assisted Reduction of Missing Values in Phosphoproteomic and Proteomic Isobaric Labeling Data Using Tandem Mass Spectrum Clustering
- Single-pot, solid-phase-enhanced sample preparation for proteomics experiments
- SP3/PAC protocol
- species redundancy
- Species–function relationships shape ecological properties of the human gut microbiome
- Spectra library search
- Spectral Clustering Improves Label-Free Quantification of Low-Abundant Proteins
- SPEED, nanodiamond
- Strategies for Increasing the Depth and Throughput of Protein Analysis by plexDIA
- streptavidin-coupled bead
- super pathway
- Surfactant-assisted one-pot sample preparation for label-free single-cell proteomics
- Systematic Evaluation of Protein Reduction and Alkylation Reveals Massive Unspecific Side Effects by Iodine-containing Reagents
- systmatic optimization of Phosphopeptide Enrichment for minute sample
- TableOfContents
- Techniques for clinical metaproteomics
- The diversity–stability debate
- The effect of peptide adsorption on signal linearity and a simple approach to improve reliability of quantification
- The guild as a concept and a means in ecological parasitology
- The Guild Concept and the Structure of Ecological Communities
- The One Hour Human Proteome
- The Simplified Human Intestinal Microbiota (SIHUMIx)
- Thilo Muth
- Ti4+-IMAC
- Tiannan Guo
- tiddlywiki grammar
- Tim Van Den Bossche
- Time to Result
- timeline for misc
- TMT cluster
- TMT for quantitative proteomics
- TMTpro reagent
- to read
- ToDo list
- training resource
- trap-and-elute
- tree of life
- Trypsin activity
- Trypsin autolysis
- two-step database search strategy
- Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition
- Unbiased Antimicrobial Resistance Detection from Clinical Bacterial Isolates Using Proteomics
- Unified Human Gut Virome Catalog (UHGV)
- Unified Workflow for the Rapid and In-Depth Characterization of Bacterial Proteomes
- uniprot: peptide index and query
- unique peptide VS distinct peptide
- Updates of the In-Gel Digestion Method for Protein Analysis by Mass Spectrometry
- Upper Limit of SDS for Tryptic Digestion
- variable conditions of MS analysis
- Virtual multi-Omics lab
- VOGDB—Database of Virus Orthologous Groups
- Weighted Kolmogorov Smirnov testing: an alternative for Gene Set Enrichment Analysis
- what bacteria housekeeping proteins can be used for normalization in metaproteimcs
- What database should mass spectrometrists search?
- What fungi live in the gut? Meet the gut mycobiome
- What is the total number of protein molecules per cell volume?
- WikiMap
- William Stafford Noble
- Yang-yu Liu
- Yangyang Bian
- µPhos in 2024
- 为什么 VS Code 会这么牛逼?
- 先验概率 与 后验概率
- 参数方法与非参数方法
- 吲哚
- 基于深度学习的搜索引擎
- 大语言模型的速度为什么需要越来越快?
- 如何鉴定新的AMR基因或protein
- 常用 AI
- 序列比对
- 序列比对工具
- 接地气的
- 数据降维
- 核密度估计
- 格雷码
- 深度学习的框架哪家强?
- 王木头人工智能笔记
- 神经科学 到深度学习
- 累积分布函数 cdf
- 线性代数与解析几何
- 细胞自动机
- 血清素
- 贝叶斯定量
- 逼近法
- 雌激素
- 音色